School of Biological Sciences

Scientists at the School of Biological Sciences have helped produce a new vaccine for foot-and-mouth disease virus (FMDV). The vaccine is all synthetic, made up of tiny protein shells designed to trigger an optimum immune response. Unlike the current vaccine it doesn't rely on growing live infectious virus so is much safer to produce. It is also easier to store than current vaccines. Crucially, this new approach to vaccines could also impact on how viruses from the same family are fought, including polio.

Professor Ian Jones and his team in the School of Biological Sciences created a form of the virus, made up of tiny empty shells, that looks exactly the same as the real virus but has no infection risk. Professor Jones said: "The shells have been altered to make them more stable and non-susceptible to the impact of warmer temperatures. The methodology used has succeeded in making this type of vaccine more efficient and reproducible for the first time. The new vaccine is unable to initiate disease so there is no possibility of accidental release and it may be less susceptible to storage conditions meaning it could be stockpiled and used in rural communities more easily. As such it could offer a substantial benefit to animal health as far as control of FMDV is concerned." 

You can read more about the research of Professor Jones and his lab on his website. 
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